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Coenzyme Q10

What is Coenzyme Q10?

Also known as ‘ubiquinone’, Coenzyme Q10 is not categorized as vitamin group
because it is subject to biosynthesis in the human body. Instead, Coenzyme Q10
is categorized as&nbsp;‘vitamin-alike
activity factor’ as it has similar effects to vitamin.&nbsp;In addition, when taken in fat-soluble
vitamin, it needs fat for intestinal absorption, Without&nbsp;fat, it will be only discharged from
the body.

Coenzyme
Q10 exists in all cells in our body, but its concentration varies depending on
tissues. In many cases, respiratory activity is mainly found in heart,&nbsp;liver,&nbsp;kidney,&nbsp;pancreas and gum, which means Coenzyme
Q10 is very important nutrient to maintain vital activity.

Meanwhile, Coenzyme Q10 decreases
together with the slow reduction in production capability during one’s 20s,
which leads to gradual aging due to weakened cell functions and the failure of
rapid generation. Therefore, this component needs to be taken for supplement.

Nutrients helpful for Coenzyme Q10
production in the human body, includes vitamin E, vitamin B2, niacin, vitamin B6,
vitamin B12, taurine, folic acid, vitamin C and selenium.

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 &nbsp;
 Biodistribution of Coenzyme Q10
 The concentration of Coenzyme Q10 is
 reduced in the body, with advancing years, which indicates that it is closely
 related to oxidation of cells. 
 &nbsp;
 Liver
 Lung
 Kidney
 Heart
 20s&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 40s&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 60s&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 80s
 &nbsp;
 </td></tr></tbody></table>

&nbsp;

Effect
of Coenzyme Q10

1. Antioxidant effect 
With its antioxidant effect, Coenzyme Q10 removes active oxygen that damages
cells, thereby helping maintain health in daily life for long time. Attacked by
active oxygen, cells lose functions or become changed in nature. Coenzyme Q10
is effective to eliminate active oxygen, thereby helping health physical
functions.

2. Energy generation and fatigue
recovery 
Coenzyme Q10 is the essential coenzymes that make the energy source named ATP
through fatty acid metabolism in cellular mitochondria. 95% of energy necessary
for human body is made through this path, to help recharge vitality.

&nbsp;

3.
Reducing blood pressure 
When Coenzyme Q10 taken, hypertensive patients showed the reducing blood
pressure both during contraction period and relaxation period.

4. Sperm activity 
Low concentration in Coenzyme Q10 and phospholipid of sperms can cause
asthenospermia and sterility. In the results of having a male sterile take
200mg of Coenzyme Q10 (twice a day) for 6 months, there was the increase in
both sperm motility and pregnancy rate.

5. Strengthened immunity 
Coenzyme Q10 is effective as a supplement for cancer prevention and AIDs cure
purposes.

6. Improved periodontitis 
Lack of Coenzyme Q10 leads to no metabolism of citric acid but accumulated in
gum, causing infection. Coenzyme Q10 reduces gum blooding and infection.

7. Anti-aging of skin 
Coenzyme Q10 has the effects to strengthen the generation of skin cells and
elasticity as well as to remove wrinkles. Also, it has whitening effect, by
inhibiting melanin.

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Related
Articles

1. Usefulness of
coenzyme Q10 in clinical cardiology: a long-term study. (Langsjoen H1,
Langsjoen P, Langsjoen P, Willis R, Folkers K. Mol Aspects Med. 1994;15
Suppl:s165-75.)

:
Coenzyme Q10 is a supplement safe and effective to cardiovascular disorders.

2. Effect of hydrosoluble coenzyme Q10 on blood
pressures and insulin resistance in hypertensive patients with coronary artery
disease. (Singh RB1, Niaz MA, Rastogi SS, Shukla PK, Thakur AS. J Hum
Hypertens. 1999 Mar;13(3):203-8.)

:
Coenzyme Q10 reduces oxidation stress, thereby lowering blood pressure.

3. Coenzyme Q10
administration and its potential for treatment of neurodegenerative diseases.
(Beal MF. Biofactors. 1999;9(2-4):261-6.)

: The
intake of Coenzyme Q10 reduces the concentration of high lactic acid of
patients with Huntington's chorea (a rare disease common during one’s 30s),
which can be used as a medicine for neurodegenerative diseases.&nbsp;

4. Effect of
coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial
infarction. (Singh RB1, Neki NS, Kartikey K, Pella D, Kumar A, Niaz MA, Thakur
AS. Mol Cell Biochem. 2003 Apr;246(1-2):75-82.)

:
Coenzyme Q10 has beneficial effects on myocardial infarction patients which
belong to high-risk group thrombosis patient category.

5. Efficacy of coenzyme Q10 on semen parameters, sperm
function and reproductive hormones in infertile men. (Safarinejad MR. J Urol.
2009 Jul;182(1):237-48. doi: 10.1016/j.juro.2009.02.121. Epub 2009 May 17.)

: There
was efficacy of Coenzyme Q10 supplement on semen parameters.

6. Effects of L-Carnitine and Coenzyme Q10 on Impaired
Spermatogenesis Caused by Isoproterenol in Male Rats. (Ghanbarzadeh S1, Garjani
A, Ziaee M, Khorrami A. Drug Res (Stuttg). 2013 Nov 27. [Epub ahead of print])

: The
intake of L-Carnitine and Coenzyme Q10 improved semen parameters impaired by
Isoproterenol (ISO).

7. Role of coenzyme Q10 (CoQ10) in cardiac disease,
hypertension and Meniere-like syndrome. (Kumar A1, Kaur H. Pharmacol Ther. 2009
Dec;124(3):259-68. doi: 10.1016/j.pharmthera.2009.07.003. Epub 2009 Jul 25.)

8. Coenzyme Q10 and cognition in atorvastatin treated
dogs. (Martin SB1, Cenini G, Barone E, Dowling AL, Mancuso C. 2011 Aug
26;501(2):92-5. doi: 10.1016/j.neulet.2011.06.054. Epub 2011 Jul 8.)

: The
concentration of Coenzyme Q10 in brain is related to improving impaired
cognition, in atorvastatin treatment.

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