Vitamin B1
14.12.05 17:18




Vitamin B1









What is vitamin B1(Thiamin) ?


As soluble one, vitamin B1 is the first vitamin acquired in pure form from vitamin B complex.

As the structure of vitamin B1 contains sulfur, the chemical name ‘thiamin’ was given after ‘thi(o+vit)amin’.

Thiamin is connected to the nitrogen-contained hexagon ring and the sulfur-contained pentagon ring located in the middle. The chemical combination of carbon in the middle of thiamin and each ring is easily destructed when exposed to heat for long time,and then it makes thiamin lose its functions.

In addition, as thiamin is not well stored, the excessive amount of intake will be immediately discharged mainly through urine.



 

Pork and peas, source of supply of vitamin B1


 


Effect of vitamin B1


1. Prevention of dementia and memory improvement

As thiamin has the effect similar to the brain neuro-transmitter called acetylcholine, it reduces the rish of improves Alzheimer’s disease, by improving memory and concentration.


2. Reduction in blood-sugar level and cholesterol

As thiamin is involved in the hydrolysis of carbohydrate, fat and protein, it performs very important role of reducing blood-sugar level and cholesterol.


3. Energy generation

Thiamin promotes proper metabolism of sugar, by helping generate energy from food.




Related Articles


1. Improved left ventricular function after thiamine supplementation in patients with congestive heart failure receiving long-term furosemide therapy. (Shimon I1, Almog S, Vered Z, Seligmann H, Shefi M, Peleg E. Am J Med. 1995 May;98(5):485-90.)

: The sufficient amount of thiamine supplementation is effective on left ventricular function improvement.


2. Preliminary findings of high-dose thiamine in dementia of Alzheimer's type. (Meador K1, Loring D, Nichols M, Zamrini E, Rivner M, Posas H. J Geriatr Psychiatry Neurol. 1993 Oct-Dec;6(4):222-9.)

: The intake of thiamine (3 g/day) is beneficial in dementia of Alzheimer’s type.


3. Role of thiamine in managing ifosfamide-induced encephalopathy. (Hamadani M1, Awan F. J Oncol Pharm Pract. 2006 Dec;12(4):237-9.)

: The role of thiamine was found to be safe and effective on ifosfamide-induced encephalopathy without adverse effects.

 



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